One of life's greatest gifts is to be able to conceive a child. Infertility can be a frustrating and frightening experience to some. It can be an emotional, psychological and physical crisis. Understanding the medical aspects as well as personal issues and becoming knowledgeable about infertility can help people cope better with many options that are there. Infertility by definition is the failure of couples to conceive in one year of trying with regular unprotected intercourse. Infertility affects 15% to 20% of all couples who are trying to conceive. The causes are many and may be associated with low sperm count, anatomic defects or disease and fallopian tube scaring are the most common factors that may cause infertility.
Causes of infertility
Ovulatory failure or dysfunction - interference or interruption at any number of points in the normal ovarian cycle could affect ovulation. The causes could be deficiency or asynchronised secretion of the controlling hormones. The ovaries may be resistant to the hormones or may be disease or damaged. Problems in ovulation lead to lack 0f menstruation (amenorrhea) or infrequent menstruation (oligomenorrhea). Lack of ovulation causes anovulatory infertility infertility in two groups: Group I: Hypothalamic pituitary failure
Group II: hypothalamic pituitary dysfunction.
Tubal Failure - the tubes may become blocked as a result of scarring due to pelvic infection, appendicitis, peritonitis or previous abdominal surgery or due to fibroids.
Endometriosis- This is a condition in which the endometrium proliferates and spreads outside the uterus. The fertility is affective depending on the severity of the condition.
Advanced Age - the fertility potential is maximum around 24 years of age. The fertility potential begins to decline by age 30 and accelerates by age 35. With advancing age there is a decline in ovaries reserve and the quality of oocytes. It is also thought that diminished endometrial receptivity with advancing age may play a role.
Luteal phase defect (LPD) - LPD occurs when the corpus luteum secretes an inadequate amount of progesterone. There are many causes for LPD but the end result is that the endometrium is not adequately prepared for implantation and nourishment of the fertilised embryo leading to infertility.
Cervical factors - cervical causes may be related to poor quality or quantity of cervical mucus, cervical stenosis and varicosities of the endocervical polyps and cervical fibroids can obstruct the os.
Others/unexplained causes - other causes are obesity, hormonal imbalances like hyperprolactinemia, hypothyroidism, immunological causes like presence of antisperm antibodies, vaginal infection and some unknown causes.
Semen containing no sperm ( azoospermia), or few sperm (oligospermia), poor quality sperm (asthenospermis) or a high percentage of abnormal sperm (teretospermia) or combination of these condition of these conditions.
Anatomic factors like varicocele, cryptorchidism and congenital anomalies like hypospadias.
Endocrine factors like cushing's disease, Acromegaly and pituitary tumor.
Infection like gonorrhea/Chlamydia, prostatitis and epididymitis.
Ejaculatory dysfunction like retrograde ejaculation, ejaculatory failure and neurologic impairment.
Immunologic factors like presence of antisperm antibodies.
- Infertility is a disease affecting the mind ,soul and the relationship of the couple
- Prompt complete workup and individualised treatment is the key to success
- With our experience we firmly belief that if patient persists with treatment,they eventually get pregnant so never ever give up hope
- Treatment of couple is our aim
- Causes of infertility