Polycystic Ovarian Disease

• Pcos is a very common problem among teen girls and young women
• Its an hormonal imbalance leading to irregular periods,weight gain ,unwanted hairs and acne.most important of all is its detrimental effect on eggs leading to infertility.
• Treatment modality in pcos has four pillars
• Diet and lifestyle changes
• Exercise
• Medical management
• Surgical management{ovarian drilling,when other options fail
• Complex interaction of genetic, metabolic, neurologic, endocrinal & environmental factors
• It starts in adolescence
• Sequelae continue even after menopause
• Prevalence 4 -10%
• Familial occurrence

Rotterdam Criteria

• Menstrual irregularity due to anovulation or oligoovulation
• Hyperandrogenism- clinical / biochemical
• Polycystic ovaries by USG- >12 follicles in each ovary,2- 9mm or ovarian volume >10mm

Pathophysiology of Polycystic Ovary Syndrome

• LH Hypothesis
• Insulin Hypothesis
• Ovarian Hypothesis