Polycystic Ovarian Disease

Polycystic Ovarian Disease

  • Pcos is a very common problem among teen girls and young women
  • Its an hormonal imbalance leading to irregular periods,weight gain ,unwanted hairs and acne.most important of all is its detrimental effect on eggs leading to infertility.
  • Treatment modality in pcos has four pillars
  • Diet and lifestyle changes
  • Exercise
  • Medical management
  • Surgical management{ovarian drilling,when other options fail
  • Complex interaction of genetic, metabolic, neurologic, endocrinal & environmental factors
  • It starts in adolescence
  • Sequelae continue even after menopause
  • Prevalence 4 -10%
  • Familial occurrence

Rotterdam Criteria

  • Menstrual irregularity due to anovulation or oligoovulation
  • Hyperandrogenism- clinical / biochemical
  • Polycystic ovaries by USG- >12 follicles in each ovary,2- 9mm or ovarian volume >10mm

Pathophysiology of Polycystic Ovary Syndrome

  • LH Hypothesis
  • Insulin Hypothesis
  • Ovarian Hypothesis